PNC-27 5mg

£129.00

PNC-27 5mg: a p53-derived HDM-2-binding peptide with a membrane-penetrating sequence, studied in cell-line research.

For laboratory research use only. Not for human or veterinary use, and not a medicine, food or cosmetic.

In stock

PNC-27 5mg research peptide

PNC-27 is a 32-amino-acid synthetic peptide. It combines residues 12–26 of the p53 protein, the region that binds HDM-2, with a membrane-penetrating leader sequence. This vial contains 5mg.

Specification

Quantity per vial5mg
Stated purity≥98%
FormLyophilised solid
Storage-20°C, sealed, protected from light and moisture

Research background

PNC-27 has been studied in cancer cell lines, where it is reported to bind HDM-2 found in the cell membrane and to cause membrane disruption. These are in-vitro and animal findings only. PNC-27 is not an approved treatment for any condition, and nothing here suggests otherwise.

Further reading: search PubMed for published studies on PNC-27.

Storage and handling

Store the vial unopened at -20°C, dry and out of direct light. Bring it to room temperature before opening so moisture does not condense on the solid. Follow your laboratory’s protocols for solvent choice and for storing any prepared solution.

Related products

PNC-27 is listed in our Specialist Research Peptides range. Related products include FOXO4-DRI 10mg (Proxofim), PTD DBM 1mg and LL-37 5mg. For reconstitution and sample storage, see our laboratory supplies.

For laboratory research use only. Not for human or veterinary use. Not a medicine, food, supplement or cosmetic.

Additional information

Molecular Formula

C188H293N53O44S

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