FOXO4-DRI 10mg (Proxofim)

£99.00

FOXO4-DRI 10mg: a D-retro-inverso peptide that disrupts FOXO4–p53 binding, used in senescent-cell (senolytic) research.

For laboratory research use only. Not for human or veterinary use, and not a medicine, food or cosmetic.

In stock

FOXO4-DRI (Proxofim) 10mg research peptide

FOXO4-DRI (sometimes called Proxofim) is a D-retro-inverso peptide. It is built from D-amino acids in reverse order, based on a region of the transcription factor FOXO4, and the D-retro-inverso design makes it resistant to proteases. This vial contains 10mg.

Specification

Quantity per vial10mg
Stated purity≥98%
FormLyophilised solid
Storage-20°C, sealed, protected from light and moisture

Research background

FOXO4-DRI was designed to disrupt the interaction between FOXO4 and p53 that helps senescent cells survive. In published mouse and cell-culture studies it caused senescent cells to undergo apoptosis selectively, making it a tool in senolytic research. It is not an approved medicine.

Further reading: search PubMed for published studies on FOXO4-DRI.

Storage and handling

On arrival, transfer the unopened vial to storage at -20°C, protected from light and moisture. Allow it to warm to room temperature before the seal is broken. Reconstitution conditions and the handling of any solution are for the receiving laboratory to set.

Related products

FOXO4-DRI is listed in our Specialist Research Peptides range. Related products include Epitalon 10mg, MOTS-C 10mg and PNC-27 5mg. For reconstitution and sample storage, see our laboratory supplies.

For laboratory research use only. Not for human or veterinary use. Not a medicine, food, supplement or cosmetic.

Additional information

Molecular Formula

C228H388N86O64

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