Orexin A 5mg research peptide
Orexin A, also called hypocretin-1, is a 33-amino-acid neuropeptide made by neurons in the lateral hypothalamus. It has an N-terminal pyroglutamate, a C-terminal amide and two intramolecular disulfide bridges. This vial contains 5mg.
Specification
| Quantity per vial | 5mg |
|---|---|
| Sequence | Pyr-Pro-Leu-Pro-Asp-Cys-Cys-Arg-Gln-Lys-Thr-Cys-Ser-Cys-Arg-Leu-Tyr-Glu-Leu-Leu-His-Gly-Ala-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Leu-NH2 (disulfide bridges 6–12 and 7–14) |
| Molecular formula | C152H243N47O44S4 |
| Molecular weight | 3561.3 g/mol |
| Stated purity | ≥98% |
| Form | Lyophilised solid |
| Storage | -20°C, sealed, protected from light and moisture |
Orexin A in neuroscience research
Orexin A binds both orexin receptors, OX1R and OX2R, with similar affinity. It is central to research on sleep–wake regulation, arousal and feeding behaviour, and loss of orexin neurons is associated with narcolepsy. Experimental work uses cell lines expressing the receptors, brain-slice preparations and animal models.
Further reading: search PubMed for published studies on Orexin A.
Storage and handling
Store the vial unopened at -20°C, dry and out of direct light. Bring it to room temperature before opening so moisture does not condense on the solid. Follow your laboratory’s protocols for solvent choice and for storing any prepared solution.
Related products
Orexin A is listed in our Neuropeptides range. Related products include Orexin B – 5mg, VIP 5mg and ACTH 1-39 5mg. For reconstitution and sample storage, see our laboratory supplies.
For laboratory research use only. Not for human or veterinary use. Not a medicine, food, supplement or cosmetic.
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